Dihydromorin, Inhibitor
Dihydromorin
Purity
98.00%
Synonyms
Dihydromorin; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C15H12O7
SMILES
O[C@H]([C@@H](c(ccc(O)c1)c1O)Oc1c2c(O)cc(O)c1)C2=O
CAS Number
18422-83-8
Target & IC50
TRP
In Vitro
But their inhibitory effects were different in two cell lines. In b16 cells, oxyresveratrol showed stronger depigmenting effect than trans- Dihydromorin, with greater suppression on tyrosinase activity. Both of them induced post-transcriptional degradations of microphthalmia-associated transcription factor (MITF), leading to significant decreases of tyrosinase related protein 1 (TRP-1) and tyrosinase related protein 2 (TRP-2) production. In melan-a cells, trans- Dihydromorin exhibited stronger inhibition on melanin synthesis. It also induced greater suppression on the levels of tyrosinase, TRP-1 and TRP-2 via MITF down-regulation at both transcription and translation level. Evaluations in artificial skin model also demonstrated the depigmenting effects of trans- Dihydromorin[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Dihydromorin, inhibitor
trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening of hypopigmenting agents.
Product Categories/Family for Dihydromorin, inhibitor
References
Oxyresveratrol and trans -dihydromorin from the twigs of Cudrania tricuspidata as hypopigmenting agents against melanogenesisJ. Funct. Foods, 2015,13:375-83.
Oxyresveratrol and trans -dihydromorin from the twigs of Cudrania tricuspidata as hypopigmenting agents against melanogenesisJ. Funct. Foods, 2015,13:375-83.
Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent.Mol. Nutr. Food Res., 2008,52(12):1530-8.
Oxyresveratrol and trans -dihydromorin from the twigs of Cudrania tricuspidata as hypopigmenting agents against melanogenesisJ. Funct. Foods, 2015,13:375-83.
Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent.Mol. Nutr. Food Res., 2008,52(12):1530-8.
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Product Notes
The Dihydromorin (Catalog #AAA5760316) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Dihydromorin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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