Structure

Delafloxacin meglumine, Inhibitor

Delafloxacin meglumine

Purity

98.00%

Synonyms

Delafloxacin meglumine; ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine; inhibitor

Ordering
Cat. Num. AAA5758994 For Research Use Only!

Purity/Purification

98.00%

Form/Format

Solid. Powder

Solubility

DMSO: 6.4mg/mL (10.06mM)
H2O: 50mg/mL (78.62mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C25H29ClF3N5O9

SMILES

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Nc1nc(c(F)cc1F)-n1cc(C(O)=O)c(=O)c2cc(F)c(N3CC(O)C3)c(Cl)c12

CAS Number

352458-37-8

Target & IC50

Antibiotic
Bacterial

In Vitro

Delafloxacin (3-15.5mg/kg) reduces lung bacterial burden in mouse models of S. aureus and S. pneumoniae lung infection[1]

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Structure

Related Product Information for Delafloxacin meglumine, inhibitor

Delafloxacin meglumine is a broad-spectrum fluoroquinolone antibiotic

Product Categories/Family for Delafloxacin meglumine, inhibitor

Microbiology/Virology; Antibiotic

References

Lepak AJ, et al. In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4764-9.
Lepak AJ, et al. In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4764-9.
Mogle, Bryan, T,et al. Clinical review of delafloxacin: a novel anionic fluoroquinolone[J]. Journal of Antimicrobial Chemotherapy, 2018.
Gena K, Kapoor E, Dasgupta A, et al. Delafloxacin meglumine for the treatment,of acute bacterial skin and skin structure infections (ABSSSI).[J]. Drugs of Today, 2018, 54:pags. 657-666.

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Product Notes

The Delafloxacin meglumine (Catalog #AAA5758994) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Delafloxacin meglumine, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Delafloxacin meglumine, Inhibitor