Structure

Cyclopentolate Hydrochloride, Inhibitor

Cyclopentolate Hydrochloride

Purity

98.28%

Synonyms

Cyclopentolate Hydrochloride; inhibitor

Ordering
Cat. Num. AAA5759187 For Research Use Only!

Purity/Purification

98.28%

Form/Format

Solid. Powder

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C17H26ClNO3

SMILES

Cl.CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1

CAS Number

5870-29-1

Target & IC50

M1: ic50 1.62nM
M2: ic50 27.5nM
M3: ic50 2.63nM

In Vitro

Cyclopentolate Hydrochloride inhibits carbachol-induced contraction of isolated human iris sphincter, circular ciliary muscle, and longitudinal ciliary muscle (Kbs = 7.9, 15.8, and 12.5nM, respectively[1].

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Structure

Related Product Information for Cyclopentolate Hydrochloride, inhibitor

Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63nM for M1, M2, and M3 receptors, respectively.

Product Categories/Family for Cyclopentolate Hydrochloride, inhibitor

Neuroscience; AChR

References

Ishikawa H, Desantis L, Patil P N. Selectivity of Muscarinic Agonists Including (+/-)-Aceclidine and Antimuscarinics on the Human Intraocular Muscles[J]. Journal of Ocular Pharmacology & Therapeutics, 1998, 14(4):363-373.
Ishikawa H, Desantis L, Patil P N. Selectivity of Muscarinic Agonists Including (+/-)-Aceclidine and Antimuscarinics on the Human Intraocular Muscles[J]. Journal of Ocular Pharmacology & Therapeutics, 1998, 14(4):363-373.
Akemi Wakayama.et al. Incidence of Side Effects of Topical Atropine Sulfate and Cyclopentolate Hydrochloride for Cycloplegia in Japanese Children: A Multicenter Study.Multicenter Study Jpn J Ophthalmol. 2018 Sep;62(5):531-536.
Akemi Wakayama.et al. Incidence of Side Effects of Topical Atropine Sulfate and Cyclopentolate Hydrochloride for Cycloplegia in Japanese Children: A Multicenter Study.Multicenter Study Jpn J Ophthalmol. 2018 Sep;62(5):531-536.

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Product Notes

The Cyclopentolate Hydrochloride (Catalog #AAA5759187) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cyclopentolate Hydrochloride, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Cyclopentolate Hydrochloride, Inhibitor