Bisabolangelone, Inhibitor
Bisabolangelone
Purity
98.00%
Synonyms
Bisabolangelone; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C15H20O3
SMILES
C[C@@]([C@@H]([C@H](CC(C)=C1)O2)C1=O)(/C2=C/C=C(C)C)O
CAS Number
30557-81-4
Target & IC50
TNF-alpha
IL Receptor
MAPK
IL Receptor
MAPK
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Bisabolangelone, inhibitor
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-kappaB signaling.
Product Categories/Family for Bisabolangelone, inhibitor
References
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.Fitoterapia. 2011 Apr;82(3):434-40.
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.Fitoterapia. 2011 Apr;82(3):434-40.
Hypopigmenting activity of bisabolangelone isolated from Angelica koreana Maxim. in alpha+/--melanocyte stimulating hormone-activated B16 or melan-a cells.Planta Med. 2011 Feb;77(3):248-51.
Kim H S, Lee Y J, Lee H K, et al. Bisabolangelone inhibits dendritic cell functions by blocking MAPK and NF-kappaB signaling[J]. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association, 2013, 59.
Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells. Int Immunopharmacol. 2010 Feb;10(2):155-62.
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.Fitoterapia. 2011 Apr;82(3):434-40.
Hypopigmenting activity of bisabolangelone isolated from Angelica koreana Maxim. in alpha+/--melanocyte stimulating hormone-activated B16 or melan-a cells.Planta Med. 2011 Feb;77(3):248-51.
Kim H S, Lee Y J, Lee H K, et al. Bisabolangelone inhibits dendritic cell functions by blocking MAPK and NF-kappaB signaling[J]. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association, 2013, 59.
Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells. Int Immunopharmacol. 2010 Feb;10(2):155-62.
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Product Notes
The Bisabolangelone (Catalog #AAA5760188) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Bisabolangelone, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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