Chemical Structure
ATI-2341 acetate, Inhibitor | ATI-2341, inhibitor
ATI-2341 acetate (1337878-62-2 free base)
Purity
0.9714
Synonyms
ATI-2341 acetate; ATI-2341 acetate (1337878-62-2 free base); ATI-2341; inhibitor
Purity/Purification
0.9714
Form/Format
Solid
Solubility
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
CCCCCCCCCCCCCCCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CCCNC(N)=N)=O)CC1=CC=C(C=C1)O)=O)CCCCN)=O)CC(O)=O)=O)[C@H](O)C)=O)CCSC)=O)CO)=O)CCCNC(N)=N)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)CCC(N)=O)=O)CC2=CC=C(C=C2)O)=O)=O)CCSC)=O.CC(O)=O
Formula
C106H182N26O27S2
In vitro
ATI-2341 induced dose-dependent peritoneal recruitment of PMNs when administered i.p. to mice. When administered systemically by i.v. bolus, ATI-2341 acted as a functional antagonist and dose-dependently mediated release of PMNs from the bone marrow of both mice and cynomolgus monkeys[1].
Preparation and Storage
Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).
Chemical Structure
Chemical Structure
Related Product Information for ATI-2341, inhibitor
ATI-2341 acetate is an effective allosteric agonist of CXCR4,it activates Galpha1 instead of Galpha13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization.
Product Categories/Family for ATI-2341, inhibitor
References
Tchernychev B, Ren Y, Sachdev P, et al. Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells[J]. Proceedings of the National Academy of Sciences of the United States of America, 2010, 107(51):p.22255-22259.
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Product Notes
The ATI-2341 (Catalog #AAA5764908) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ATI-2341 acetate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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