Structure

Apigenin-7-glucuronide, Inhibitor

Apigenin-7-glucuronide

Purity

99.27%

Synonyms

Apigenin-7-glucuronide; Apigenin 7-O-glucuronide; inhibitor

Ordering
Cat. Num. AAA5752265 For Research Use Only!

Purity/Purification

99.27%

Form/Format

Powder

Formula

C21H18O11

CAS

29741-09-1

Smiles

O[C@H]1[C@H](Oc2cc(O)c3c(c2)oc(cc3=O)-c2ccc(O)cc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O

Receptor (IC50)

MMP-3: 12.87uM
mMP-8: 22.39uM
mMP-9: 17.52uM
mMP-13: 0.27uM

Solubility

DMSO: 50mg/mL (112.02mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Structure

Related Product Information for Apigenin-7-glucuronide, inhibitor

Apigenin-7-glucuronide possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibitmMP activities (IC50s: 12.87, 22.39, 17.52, 0.27uM formMP-3,mMP-8,mMP-9,mMP-13, respectively).

Product Categories/Family for Apigenin-7-glucuronide, inhibitor

Home; Proteases/Proteasome; mMP

References

1. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83 (11):901-911.
2. Hu W, et al. Apigenin-7-O-beta-D-glucuronide inhibits LPS-induced inflammation through the inactivation of AP-1 and MAPK signaling pathways in RAW 264.7 macrophages and protects mice against endotoxin shock. Food Funct. 2016 Feb;7 (2):1002-13.
3. Deng W, et al. Scutellarin inhibits human renal cancer cell proliferation and migration via upregulation of PTEN. Biomed Pharmacother. 2018 Nov;107:1505-1513.

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Product Notes

The Apigenin-7-glucuronide (Catalog #AAA5752265) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Apigenin-7-glucuronide, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Apigenin-7-glucuronide, Inhibitor