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Chemical Structure

AMD3100 (Plerixafor), Inhibitor

AMD3100 (Plerixafor)

Purity
>98%
Synonyms
AMD3100 (Plerixafor); inhibitor
Ordering
For Research Use Only!
Purity/Purification
>98%
Form/Format
Powder
Concentration
0.1 mM: 19.89 mL (1 mg); 99.45 mL (5 mg); 198.89mL (10 mg)
0.5 mM: 3.98 mL (1 mg); 19.89 mL (5 mg); 39.78 mL (10 mg)
1 mM: 1.99 mL (1 mg); 9.94 mL (5 mg); 19.89 mL (10 mg)
5 mM: 0.4 mL (1 mg); 1.99 mL (5 mg); 3.98 mL (10 mg) (varies by lot)
CAS Number
110078-46-1
Formula
C28H54N8
SMILES
C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3
Actions
Antagonist
In Vivo Solvent
30% propylene glycol, 5% Tween 80, 65% D5W
Solubility (DMSO)
<1 mg/mL (<1 mM)
Solubility (Ethanol)
100 mg/mL (198.89 mM)
Solubility (in vivo)
30 mg/mL
Solubility (Water)
3 mg/mL heating (5.96 mM)
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.
Preparation and Storage
at -20 degree C 3 years Powder

Chemical Structure

Chemical Structure
Related Product Information for AMD3100 (Plerixafor), inhibitor
Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.
References
Ichimizu S, .et al. Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape, J Control Release, 2019, May 10;304:156-163 PMID: 31082432
Nan Li, .et al. LPS-induced CXCR7 expression promotes gastric Cancer proliferation and migration via the TLR4/MD-2 pathway, Diagn Pathol, 2019, Jan 12;14(1):3 PMID: 30636642
Thida W, .et al. The role of conventional antibodies targeting the CD4 binding site and CD4-induced epitopes in the control of HIV-1 CRF01_AE viruses, Biochem Biophys Res Commun, 2018, Nov 20. pii: S0006-291X(18)32477-X PMID: 30470571
Henry R. Hampton, .et al. Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes, Nat Commun, 2015, 6: 7139 PMID: 25972253

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Product Notes

The AMD3100 (Plerixafor) (Catalog #AAA385227) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AMD3100 (Plerixafor), Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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