Alismol, Inhibitor
Alismol
Purity
98.00%
Synonyms
Alismol; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C15H24O
SMILES
CC(C)C(CCC([C@H]1CC2)=C)=C[C@H]1[C@]2(C)O
CAS Number
87827-55-2
Target & IC50
Calcium Channel
Potassium Channel
PI3K
Potassium Channel
PI3K
In Vitro
Alismol (10(-6) to 10(-4) M) inhibited the contraction of isolated rabbit ear artery by electrical stimulation of the perivascular nerves. The inhibition was concentration-dependent; at a concentration of 10(-4) M, the inhibition was 90% (n = 8). treatment with 10(-4) M Alismol inhibited the increase in 3H-noradrenaline (3H-NAd) release induced by electrical stimulation by 63 +/- 6%. Alismol at 10(-4) M did not affect the neuronal uptake of 3H-NAd in the artery. Alismol at 10(-4) M slightly inhibited contractions induced by exogenously administered NAd[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Alismol, inhibitor
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.
Product Categories/Family for Alismol, inhibitor
References
Effect of alismol on adrenergic mechanism in isolated rabbit ear artery.Jpn J Pharmacol. 1988 Apr;46(4):331-5.
Effect of alismol on adrenergic mechanism in isolated rabbit ear artery.Jpn J Pharmacol. 1988 Apr;46(4):331-5.
Effects of alismol isolated from Alismatis Rhizoma on calcium-induced contraction in the rabbit thoracic aorta.Life Sci. 1987 Oct 12;41(15):1845-52.
Effect of alismol isolated from Alismatis Rhizoma on working heart perfusion in rat. Phytother. Res., 1989, 3(2):72-4.
Effect of alismol on adrenergic mechanism in isolated rabbit ear artery.Jpn J Pharmacol. 1988 Apr;46(4):331-5.
Effects of alismol isolated from Alismatis Rhizoma on calcium-induced contraction in the rabbit thoracic aorta.Life Sci. 1987 Oct 12;41(15):1845-52.
Effect of alismol isolated from Alismatis Rhizoma on working heart perfusion in rat. Phytother. Res., 1989, 3(2):72-4.
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Product Notes
The Alismol (Catalog #AAA5760111) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Alismol, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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