Human interleukin enhancer binding factor 2, 45kDa ELISA Kit | ILF2 elisa kit
Human Interleukin enhancer-binding factor 2, ILF2/NF45/PRO3063 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is the 45 kDa component of nuclear factor of activated T-cells (NFAT), a heterodimer of 45 kDa and 90 kDa proteins. NFAT is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The complex has been shown to repair DNA breaks by nonhomologous end joining and can also negatively regulate the microRNA processing pathway. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Jun 2012]
Uniprot Description
ILF2: Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.
Protein type: Transcription, coactivator/corepressor; Nucleolus; RNA-binding
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; ribonucleoprotein complex; nucleus
Molecular Function: transferase activity; protein binding; DNA binding; double-stranded RNA binding; ATP binding
Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; immune response
Research Articles on ILF2
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Product Notes
The Human ILF2 ilf2 (Catalog #AAA9310733) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9310733 ELISA Kit recognizes Human ILF2. It is sometimes possible for the material contained within the vial of "interleukin enhancer binding factor 2, 45kDa, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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