Western Blot (WB)
(Western blot analysis of IL-36B in A549 cell lysate with IL-36B antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
IL-36G Blocking Peptide | IL36G blocking peptide
IL-36G Peptide
Western Blot (WB)
(Western blot analysis of IL-36B in A549 cell lysate with IL-36B antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of IL-36B in A549 cell lysate with IL-36B antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
Uniprot Description
Il1f9: Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytokine
Chromosomal Location of Human Ortholog: 2q12-q21
Cellular Component: extracellular space
Molecular Function: interleukin-1 receptor binding; cytokine activity
Biological Process: cell-cell signaling; cytokine and chemokine mediated signaling pathway; innate immune response; positive regulation of interleukin-6 production; inflammatory response; negative regulation of myoblast differentiation
Research Articles on IL36G
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Product Notes
The IL36G il36g (Catalog #AAA153777) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IL-36G can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). The peptide is used for blocking the activity of IL-36G antibody. It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37 degree C. Researchers should empirically determine the suitability of the IL36G il36g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-36G, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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