Interleukin 33 (IL33) Recombinant Protein | IL33 recombinant protein

Recombinant Interleukin 33 (IL33)

Cat. Num. AAA2124539

• Gene Names: Il33; Il-33; Il1f11; NF-HEV; 9230117N10Rik
• Applications: SDS-Page, Western Blot
• Purity: >97%
• Synonyms: Interleukin 33 (IL33); Recombinant Interleukin 33 (IL33); Interleukin 33; DV27; C9ORF26; IL1F11; NFHEV; Interleukin-1 Family; Member 11; Nuclear factor from high endothelial venules; IL33 recombinant protein

• Host: E Coli
• Purity/Purification: >97%
• Form/Format: Freeze-dried powder; PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Sequence: Met1~Ile266

• Applicable Applications for IL33 recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Source: Prokaryotic expression
• Species: Mouse
• Tag: N-terminal His Tag
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Usage: Reconstitute in PBS or others.
• Preparation and Storage: Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Product Categories/Family for IL33 recombinant protein

Cytokine; Infection immunity; Recombinant proteins/RP

NCBI and Uniprot Product Information

• NCBI GI #: 257900495
• NCBI GeneID: 77125
• NCBI Accession #: NP_001158196.1
• NCBI GenBank Nucleotide #: NM_001164724.1
• UniProt Accession #: Q8BVZ5; Q2YEJ4; Q3TQN0; Q99L46
• Molecular Weight: 29,991 Da
• NCBI Official Full Name: interleukin-33
• NCBI Official Synonym Full Names: interleukin 33
• NCBI Official Symbol: Il33
• NCBI Official Synonym Symbols: Il-33; Il1f11; NF-HEV; 9230117N10Rik
• NCBI Protein Information: interleukin-33
• UniProt Protein Name: Interleukin-33
• Protein Family: Interleukin
• UniProt Gene Name: Il33
• UniProt Synonym Gene Names: IL-33
• UniProt Entry Name: IL33_MOUSE

Uniprot Description

IL33: Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T-helper type 2-associated cytokines. Belongs to the IL-1 family. Highly divergent. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Cellular Component: nucleus

Molecular Function: cytokine activity

Biological Process: defense response to virus; macrophage activation during immune response; microglial cell activation during immune response; negative regulation of immunoglobulin secretion; negative regulation of interferon-gamma production; negative regulation of leukocyte migration; negative regulation of T-helper 1 type immune response; positive regulation of immunoglobulin secretion; positive regulation of inflammatory response; positive regulation of interleukin-13 production; positive regulation of interleukin-4 production; positive regulation of interleukin-5 production; positive regulation of interleukin-6 production; positive regulation of macrophage activation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of T-helper 2 type immune response; positive regulation of transcription from RNA polymerase II promoter