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Interleukin-1 receptor type 2 (Il1r2) Recombinant Protein | Il1r2 recombinant protein

Recombinant Rat Interleukin-1 receptor type 2 (Il1r2)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Interleukin-1 receptor type 2 (Il1r2); Recombinant Rat Interleukin-1 receptor type 2 (Il1r2); Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD_antigen=; CD121bCleaved into the following 2 chains:; 1. Inte; Il1r2 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
14-355
Sequence
FTTPAVV HTGRVSESPV TSEKHPVLGD DCWFRGRDFK SELRLEGEPV VLRCPLVPHS DTSSSSRSLL TWSKSDSSQL IPGDEPRMWV KDDTLWVLPA VQQDSGTYIC TFRNASHCEQ MSLELKVFKN TEASFPLVSY LQISALSSTG LLVCPDLKEF ISSRTDGKIQ WYKGSILLDK GNKKFLSAGD PTRLLISNTS MGDAGYYRCV MTFTYEGKEY NITRNIELRV KGITTEPIPV IISPLETIPA SLGSRLIVPC KVFLGTGTSS NTIVWWMANS TFISVAYPRG RVTEGLHHQY SENDENYVEV SLIFDPVTKE DLNTDFKCVA TNPRSFQSLH TTVKE
Sequence Length
342
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,353 Da
NCBI Official Full Name
interleukin-1 receptor type 2
NCBI Official Synonym Full Names
interleukin 1 receptor, type II
NCBI Official Symbol
Il1r2
NCBI Protein Information
interleukin-1 receptor type 2; IL-1R-2; IL-1RT2; IL-1RT-2; IL-1R-beta; IL-1 type II receptor; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B
UniProt Protein Name
Interleukin-1 receptor type 2
Protein Family
UniProt Gene Name
Il1r2
UniProt Synonym Gene Names
Il-1r2; Il1rb; IL-1R-2; IL-1RT-2; IL-1RT2; IL-1R-beta; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII
UniProt Entry Name
IL1R2_RAT

NCBI Description

receptor for IL-1 alpha and IL-1 beta [RGD, Feb 2006]

Uniprot Description

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors ().

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Product Notes

The Il1r2 il1r2 (Catalog #AAA949580) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 14-355. The amino acid sequence is listed below: FTTPAVV HTGRVSESPV TSEKHPVLGD DCWFRGRDFK SELRLEGEPV VLRCPLVPHS DTSSSSRSLL TWSKSDSSQL IPGDEPRMWV KDDTLWVLPA VQQDSGTYIC TFRNASHCEQ MSLELKVFKN TEASFPLVSY LQISALSSTG LLVCPDLKEF ISSRTDGKIQ WYKGSILLDK GNKKFLSAGD PTRLLISNTS MGDAGYYRCV MTFTYEGKEY NITRNIELRV KGITTEPIPV IISPLETIPA SLGSRLIVPC KVFLGTGTSS NTIVWWMANS TFISVAYPRG RVTEGLHHQY SENDENYVEV SLIFDPVTKE DLNTDFKCVA TNPRSFQSLH TTVKE. It is sometimes possible for the material contained within the vial of "Interleukin-1 receptor type 2 (Il1r2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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