Typical Testing Data/Standard Curve (for reference only)
(Mouse IL-17RC PicoKine ELISA Kit standard curve )
Mouse IL-17RC ELISA Kit | IL17RC elisa kit
Mouse IL-17RC PicoKine ELISA Kit
Gene Names
Il17rc; Il17rl; Gm19850; IL-17RC; IL17-RC; IL17-RL; 1110025H02Rik
Reactivity
Mouse
Synonyms
IL-17RC; Mouse IL-17RC PicoKine ELISA Kit; Interleukin-17 receptor C; interleukin 17 receptor C; IL 17 receptor C; IL 17RC; IL 17RL; IL17 receptor C; IL17F receptor; IL17RL; Interleukin 17 receptor C; Interleukin 17 receptor homolog; Interleukin 17 receptor like; Interleukin 17 receptor like protein; IL17RC elisa kit
Reactivity
Mouse
Specificity
Natural and recombinant mouse IL-17RC
Sequence Length
674
Samples
Cell culture supernates, serum and plasma (heparin, EDTA)
Assay Type
Sandwich
Detection Range
156pg/ml-10,000pg/ml
Sensitivity
< 10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Typical Testing Data/Standard Curve (for reference only)
(Mouse IL-17RC PicoKine ELISA Kit standard curve )
Typical Testing Data/Standard Curve (for reference only)
(Mouse IL-17RC PicoKine ELISA Kit standard curve )
Related Product Information for IL17RC elisa kit
Principle of the assay: mouse IL-17RC ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for IL-17RC has been precoated onto 96-well plates. Standards(NSO, E22-R440) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for IL-17RC is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse IL-17RC amount of sample captured in plate.
Background: Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene. By genomic sequence analysis, IL17RC gene was mapped to chromosome 3p25.3-p24.1. This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date. The biologic activity of IL-17 is dependent on a complex composed of IL-17RA and IL-17RC, suggesting a new paradigm for understanding the interactions between the expanded family of IL-17 ligands and their receptors.
Background: Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene. By genomic sequence analysis, IL17RC gene was mapped to chromosome 3p25.3-p24.1. This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date. The biologic activity of IL-17 is dependent on a complex composed of IL-17RA and IL-17RC, suggesting a new paradigm for understanding the interactions between the expanded family of IL-17 ligands and their receptors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
62,798 Da
NCBI Official Full Name
Interleukin-17 receptor C
NCBI Official Synonym Full Names
interleukin 17 receptor C
NCBI Official Symbol
Il17rc
NCBI Official Synonym Symbols
Il17rl; Gm19850; IL-17RC; IL17-RC; IL17-RL; 1110025H02Rik
NCBI Protein Information
interleukin-17 receptor C; IL-17RL; zcytoR14; IL-17 receptor C; interleukin-17 receptor-like protein
UniProt Protein Name
Interleukin-17 receptor C
Protein Family
UniProt Gene Name
Il17rc
UniProt Synonym Gene Names
IL-17 receptor C; IL-17RC; IL-17RL
UniProt Entry Name
I17RC_MOUSE
Uniprot Description
IL17RC: a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
Protein type: Membrane protein, integral
Cellular Component: membrane; integral to plasma membrane; integral to membrane; plasma membrane
Molecular Function: protein binding; interleukin-17 receptor activity
Biological Process: cytokine and chemokine mediated signaling pathway
Research Articles on IL17RC
Similar Products
Product Notes
The Mouse IL17RC il17rc (Catalog #AAA177348) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA177348 ELISA Kit recognizes Mouse IL17RC. It is sometimes possible for the material contained within the vial of "IL-17RC, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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