Chicken Interleukin 7 ELISA Kit | IL-7 elisa kit

Chicken Interleukin 7 ELISA Kit

Cat. Num. AAA734777

• Gene Names: IL7; IL-7
• Reactivity: Chicken
• Synonyms: Interleukin 7; Chicken Interleukin 7 ELISA Kit; IL-7 elisa kit

• Reactivity: Chicken

• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Product Categories/Family for IL-7 elisa kit

Immunology

NCBI and Uniprot Product Information

• NCBI GI #: 315467871
• NCBI GeneID: 3574
• NCBI Accession #: NP_001186817.1
• NCBI GenBank Nucleotide #: NM_001199888.1
• UniProt Accession #: Q5FBX5; P13232; Q5FBY3; Q5FBY5; Q5FBY6; Q5FBY8
• Molecular Weight: 13,370 Da
• NCBI Official Full Name: interleukin-7 isoform 4
• NCBI Official Synonym Full Names: interleukin 7
• NCBI Official Symbol: IL7
• NCBI Official Synonym Symbols: IL-7
• NCBI Protein Information: interleukin-7
• UniProt Protein Name: IL7 nirs variant 1
• UniProt Gene Name: IL7
• UniProt Entry Name: Q5FBX5_HUMAN

NCBI Description

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]

Uniprot Description

IL7: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Secreted, signal peptide; Secreted; Cytokine; Cell development/differentiation; Cell cycle regulation

Chromosomal Location of Human Ortholog: 8q12-q13

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-7 receptor binding; protein binding; growth factor activity; cytokine activity

Biological Process: positive regulation of organ growth; humoral immune response; T cell lineage commitment; organ morphogenesis; positive regulation of T cell differentiation; cell-cell signaling; regulation of gene expression; homeostasis of number of cells within a tissue; negative regulation of catalytic activity; positive regulation of cell proliferation; positive regulation of B cell proliferation; bone resorption; negative regulation of apoptosis