Typical Testing Data/Standard Curve (for reference only)
Mouse DNA-binding protein Ikaros ELISA Kit | Ikzf1 elisa kit
Mouse DNA-binding protein Ikaros ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
Ikaros: a transcription factor of the ikaros C2H2-type zinc-finger protein family. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Functions in the specification and the maturation of the T-lymphocyte. Also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development. Deletions in Ikaros have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Seven alternatively spliced human isoforms have been described.
Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding
Cellular Component: centric heterochromatin; cytoplasm; nucleus; protein complex; transcription factor complex
Molecular Function: DNA binding; metal ion binding; nucleic acid binding; poly-pyrimidine tract binding; protein binding; protein heterodimerization activity; sequence-specific DNA binding; transcription factor activity
Biological Process: B cell differentiation; cell cycle; chromatin modification; erythrocyte differentiation; establishment of protein localization; forebrain development; gland development; hemopoiesis; lymph node development; lymphocyte differentiation; multicellular organismal development; natural killer cell differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; Peyer's patch development; positive regulation of B cell differentiation; positive regulation of multicellular organism growth; positive regulation of neutrophil differentiation; positive regulation of NK T cell differentiation; positive regulation of RNA elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of transcriptional preinitiation complex assembly; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; retina development in camera-type eye; retinal bipolar neuron differentiation; T cell differentiation; thymus development; transcription, DNA-dependent
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Product Notes
The Mouse Ikzf1 ikzf1 (Catalog #AAA2881333) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881333 ELISA Kit recognizes Mouse Ikzf1. It is sometimes possible for the material contained within the vial of "DNA-binding protein Ikaros, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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