NF-kappa-B essential modulator (IKBKG) Recombinant Protein | IKBKG recombinant protein
Recombinant Bovine NF-kappa-B essential modulator (IKBKG)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
NF-kappa-B essential modulator (IKBKG); Recombinant Bovine NF-kappa-B essential modulator (IKBKG); IKBKG recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-419, full length protein
Sequence
MSRPPWKSPLCEMVQPSGSPAGDQDMLGEESSLGKPAMLHVPSEQGTPETFQRCLEENQELRDAIRQSNQMLRERCEELQHFQGNQREEKAFLMQKFQEARDLVVRLSLEKRELRQQREQALKEVERLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRARVASEKARQLESEREALEQRHSVQVDQLVLQNESMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHMKSSMVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKEFLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPPLAPGPAHHSFHLNPSSQRRSPPDEPPKFCCPKCQYQAPDIDTLQIHVMECIE
Sequence Length
419
Species
Bovine
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,570 Da
NCBI Official Full Name
NF-kappa-B essential modulator
NCBI Official Synonym Full Names
inhibitor of nuclear factor kappa B kinase subunit gamma
NCBI Official Symbol
IKBKG
NCBI Protein Information
NF-kappa-B essential modulator
UniProt Protein Name
NF-kappa-B essential modulator
UniProt Gene Name
IKBKG
UniProt Synonym Gene Names
NEMO; NEMO; IKKAP1; I-kappa-B kinase subunit gamma; IKK-gamma; IKKG; IkB kinase subunit gamma
Uniprot Description
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination ().
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Product Notes
The IKBKG ikbkg (Catalog #AAA1349549) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-419, full length protein. The amino acid sequence is listed below: MSRPPWKSPL CEMVQPSGSP AGDQDMLGEE SSLGKPAMLH VPSEQGTPET FQRCLEENQE LRDAIRQSNQ MLRERCEELQ HFQGNQREEK AFLMQKFQEA RDLVVRLSLE KRELRQQREQ ALKEVERLKT CQQQMAEDKA SVKAQVTSLL GELQESQSRL EAATKERQAL ESRARVASEK ARQLESEREA LEQRHSVQVD QLVLQNESME AALRMERQAA SEEKRKLAQL QVAYHQLFQE YDNHMKSSMV SSERNRGLQL EDLKQQLQQA EEALVAKQEV IDKLKEEAEQ HKIVMETVPV LKAQADIYKA DFQAERQARE KLAEKKEFLQ EQLEQLQREY SRLKTSCQES ARIEDMRKRH VEVSQPPLAP GPAHHSFHLN PSSQRRSPPD EPPKFCCPKC QYQAPDIDTL QIHVMECIE. It is sometimes possible for the material contained within the vial of "NF-kappa-B essential modulator (IKBKG), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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