Mouse Inhibitor of nuclear factor kappa-B kinase subunit epsilon ELISA Kit | Ikbke elisa kit
Mouse Inhibitor of nuclear factor kappa-B kinase subunit epsilon ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
IKKE: a oncogenic kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Plays a pivotal role in coordinating the activation of IRF3 and NF-kappaB in the innate immune response. Its redistribution to PML nuclear bodies upon DNA damage is TOPORS-dependent. Is a breast cancer oncogene that exerts its oncogenic properties through cRel.
Protein type: Kinase, protein; EC 2.7.11.10; Inhibitor; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Other group; IKK family
Cellular Component: cytoplasm; mitochondrial membrane; nucleus; PML body
Molecular Function: ATP binding; IkappaB kinase activity; kinase activity; NF-kappaB-inducing kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; ubiquitin protein ligase binding
Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; phosphorylation; protein amino acid phosphorylation; protein homooligomerization; response to DNA damage stimulus
Research Articles on Ikbke
Similar Products
Product Notes
The Mouse Ikbke ikbke (Catalog #AAA2881404) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881404 ELISA Kit recognizes Mouse Ikbke. It is sometimes possible for the material contained within the vial of "Inhibitor of nuclear factor kappa-B kinase subunit epsilon, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.