Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

SDS-PAGE

PGRL / IGSF8 recombinant protein

Recombinant Mouse PGRL / IGSF8 Protein (His tag)

Gene Names
Igsf8; PGRL; EWI-2; KCT-4; ESTM34
Purity
> 95 % as determined by SDS-PAGE
Synonyms
PGRL / IGSF8; Recombinant Mouse PGRL / IGSF8 Protein (His tag); IGSF8; Ewi2; Kct4; Pgrl; PGRL / IGSF8 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
611
Application Notes
The recombinant mouse IGSF8 comprises 563 amino acids and has a predicted molecular mass of 60.2 kDa. The apparent molecular mass of the protein is approximately 66 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Arg 26
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for PGRL / IGSF8 recombinant protein
A DNA sequence encoding the mouse IGSF8 (AAH48387.1) (Met1-Thr577) was expressed with a C-terminal polyhistidine tag.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
65,011 Da
NCBI Official Full Name
Immunoglobulin superfamily, member 8
NCBI Official Synonym Full Names
immunoglobulin superfamily, member 8
NCBI Official Symbol
Igsf8
NCBI Official Synonym Symbols
PGRL; EWI-2; KCT-4; ESTM34
NCBI Protein Information
immunoglobulin superfamily member 8
UniProt Protein Name
Immunoglobulin superfamily member 8
UniProt Gene Name
Igsf8
UniProt Synonym Gene Names
Ewi2; Kct4; Pgrl; IgSF8; EWI-2; KCT-4; PGRL

Uniprot Description

IGSF8: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin- dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1 H3|1 79.59 cM

Cellular Component: axon; integral to membrane; membrane; myelin sheath; plasma membrane; synapse

Molecular Function: protein binding

Research Articles on PGRL / IGSF8

Similar Products

Product Notes

The PGRL / IGSF8 igsf8 (Catalog #AAA2546683) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse IGSF8 comprises 563 amino acids and has a predicted molecular mass of 60.2 kDa. The apparent molecular mass of the protein is approximately 66 kDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the PGRL / IGSF8 igsf8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGRL / IGSF8, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.