Insulin Like Growth Factor Binding Protein 6 (IGFBP6) Recombinant Protein | IGFBP6 recombinant protein

Recombinant Insulin Like Growth Factor Binding Protein 6 (IGFBP6)

Cat. Num. AAA2009045

• Gene Names: Igfbp6; RBP6A; IGF-BP6
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Insulin Like Growth Factor Binding Protein 6 (IGFBP6); Recombinant Insulin Like Growth Factor Binding Protein 6 (IGFBP6); IGFBP6 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-ETGGCFRREG QPCGVYIPKC APGLQCQPRE NEETPLRALL IGQGRCQRAR GPSEETTKES KPHGGASRPR DRDRQKNPRT SAAPIRPSPV QDGEMGPCRR HLDSVLQQLQ TEVFRGGANG LYVPNCDLRG FYRKQQCRSS QGNRRGPCWC VDPMGQPLPV SPDGQGSSQC SARSSG
• Sequence Length: 226

• Applicable Applications for IGFBP6 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Rattus norvegicus (Rat)
• Expression System: Prokaryotic expression
• Residues: Glu51~Gly226 (Accession # P35572) with two N-terminal Tags, His-tag and T7-tag
• Subcellular Location: Secreted
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Predicted Isoelectric Point: 9.5
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 6981090
• NCBI GeneID: 25641
• NCBI Accession #: NP_037236.1
• NCBI GenBank Nucleotide #: NM_013104.3
• UniProt Accession #: P35572; Q499W1
• Molecular Weight: 23.1kDa
• NCBI Official Full Name: insulin-like growth factor-binding protein 6
• NCBI Official Synonym Full Names: insulin-like growth factor binding protein 6
• NCBI Official Symbol: Igfbp6
• NCBI Official Synonym Symbols: RBP6A; IGF-BP6
• NCBI Protein Information: insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IGF-binding protein 6
• UniProt Protein Name: Insulin-like growth factor-binding protein 6
• Protein Family: Insulin-like growth factor-binding protein
• UniProt Gene Name: Igfbp6
• UniProt Synonym Gene Names: Igfbp-6; IBP-6; IGF-binding protein 6; IGFBP-6
• UniProt Entry Name: IBP6_RAT

NCBI Description

high-affinity IGF binding ptotein with substantially greater affinity for insulin-like growth factor-II (IGF-II) than IGF-I [RGD, Feb 2006]

Uniprot Description

Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Subcellular location: Secreted.

Post-translational modification: O-glycosylated.

Sequence similarities: Contains 1 IGFBP N-terminal domain.Contains 1 thyroglobulin type-1 domain.