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Interferon-beta Recombinant Protein | mIFNB recombinant protein

Recombinant Mouse Interferon-beta

Gene Names
Ifnb1; Ifb; IFNB; IFN-beta
Purity
Greater than 95% as determined by Analysis by SDS-PAGE.
Synonyms
Interferon-beta; Recombinant Mouse Interferon-beta; IFN b Mouse; His; Interferon Beta Mouse Recombinant; His Tag; Leukocyte interferon; B cell interferon; Type I interferon; IFNB1; IFB; IFF; IFNB; IFN-b 1b; MGC96956; mIFNB recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95% as determined by Analysis by SDS-PAGE.
Form/Format
The IFN-Beta (0.25mg/ml) contains 20mM HEPES (pH6.0), 0.5M NaCl & 10% glycerol.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN
Sequence Length
182
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for mIFNB recombinant protein
Description: Interferon beta Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (22-182 a.a.) and having a molecular mass of 22 kDa. Mouse IFN beta is fused to 20 amino acid at N-terminus and purified by proprietary chromatographic techniques.

Introduction: Interferon-beta 1b has antiviral, antibacterial and anticancer activities.Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein.Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.
Product Categories/Family for mIFNB recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,127 Da
NCBI Official Full Name
interferon beta
NCBI Official Synonym Full Names
interferon beta 1, fibroblast
NCBI Official Symbol
Ifnb1
NCBI Official Synonym Symbols
Ifb; IFNB; IFN-beta
NCBI Protein Information
interferon beta
UniProt Protein Name
Interferon beta
UniProt Gene Name
Ifnb1
UniProt Synonym Gene Names
Ifb; Ifnb; IFN-beta
UniProt Entry Name
IFNB_MOUSE

Uniprot Description

IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; defense response; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; defense response to virus; B cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein

Research Articles on mIFNB

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Product Notes

The mIFNB ifnb1 (Catalog #AAA143787) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN. It is sometimes possible for the material contained within the vial of "Interferon-beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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