Typical Testing Data/Standard Curve (for reference only)
Mouse IFN beta ELISA Kit | IFNB1 elisa kit
Mouse IFN beta ELISA Kit
Gene Names
Ifnb1; Ifb; IFNB; IFN-beta
Reactivity
Mouse
Synonyms
IFN beta; Mouse IFN beta ELISA Kit; IFB; IFNB; Interferon beta; IFN-beta; Fibroblast interferon; IFNB1 elisa kit
Reactivity
Mouse
Specificity
The Mouse IFN beta ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse IFN beta proteins within the range of 12.5 pg/ml - 800 pg/ml.
Sequence Length
182
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<6 pg/ml
Preparation and Storage
Store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for IFNB1 elisa kit
Principle of the Assay: MBS Mouse IFN beta ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse IFN beta in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Mouse IFN beta coated on a 96-well plate. Standards and samples are pipetted into the wells and IFN beta present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse IFN beta antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IFN beta bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.!!Background/Introduction: Interferons (IFNs) appear both locally and systematically early after viral infection and participate in limiting the spread of infection; they also affect cell differentiation, growth, surface antigen expression and immunoregulation. There are three naturally occurring interferons: alpha, beta and gamma. IFN-alpha is derived from lymphoblastic tissue and has a number of therapeutic applications in the treatment of various human cancers and diseases of viral origin. When binding to discrete cell surface receptors on target cells, IFN-alpha induces rapid changes in Jak/Stat phosphorylation, which intiates the Jak/Stat signaling pathway. IFN-alpha signaling also involves production of DAG without an increased intracellular free calcium concentration and the subsequent activation of calcium-independent isoforms of PKC (beta and epsilon). All IFN-alpha signaling pathways lead to final alterations of gene expression, which mediate their pleiotropic biologic activities.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,127 Da
NCBI Official Full Name
interferon beta
NCBI Official Synonym Full Names
interferon beta 1, fibroblast
NCBI Official Symbol
Ifnb1
NCBI Official Synonym Symbols
Ifb; IFNB; IFN-beta
NCBI Protein Information
interferon beta
UniProt Protein Name
Interferon beta
Protein Family
UniProt Gene Name
Ifnb1
UniProt Synonym Gene Names
Ifb; Ifnb; IFN-beta
Uniprot Description
Has antiviral, antibacterial and anticancer activities.
Research Articles on IFNB1
Similar Products
Product Notes
The Mouse IFNB1 ifnb1 (Catalog #AAA8291413) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8291413 ELISA Kit recognizes Mouse IFNB1. It is sometimes possible for the material contained within the vial of "IFN beta, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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