Interferon-induced protein 44-like (IFI44L) Recombinant Protein | IFI44L recombinant protein

Recombinant Mouse Interferon-induced protein 44-like (IFI44L)

Cat. Num. AAA1445336

• Gene Names: Ifi44l; H28; H-28; H28-1; NS1178
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Interferon-induced protein 44-like (IFI44L); Recombinant Mouse Interferon-induced protein 44-like (IFI44L); IFI44L recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-447, full length protein
• Sequence: MKVTARLTWIEEKILEKLLGNASLTLLYQSSAHKNCVSEMTQKYSLQGSTMTVFHLEKDVVVGVFILENFPRLVSEKPCTCAWFSLKRNNSSGISALFLNTKVIVDSEELIIFSLDGLSLSVTPLRGFTLALNDTVMNGLELNLGHGFLPVECEIFRVDGIKKNPSFIKKMVTAEQHRGKLLSALRAYKPYKDLVSEVRILLVGPVGSGKSSFFNSVKSAFQGHLTRQAIVGSDESSITKQYRVYSIKDGKSGETLPFMLCDSMGLEEGEEAGLCIDDIPHILQGCVPDRYQFNPCEPMKPKHSPHAASPPLKDRIHCVAFVLHINSVNTLSDKMVAKLKKIRKDVVDCGIGYVALLTNVEEYDEVLDDSFANMTETVTSLSQVQNVQKWLNIPIANILMVSNYASERRLEPMKDILVFAALRQMLRAADDALEDLPLEDTGNLAPF
• Sequence Length: 447

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 13811697
• NCBI GeneID: 15061
• NCBI Accession #: NP_112735.1
• NCBI GenBank Nucleotide #: NM_031367.1
• UniProt Accession #: Q9BDB7; Q8SP46
• Molecular Weight: 44,004 Da
• NCBI Official Full Name: interferon-induced protein 44-like
• NCBI Official Synonym Full Names: interferon-induced protein 44 like
• NCBI Official Symbol: Ifi44l
• NCBI Official Synonym Symbols: H28; H-28; H28-1; NS1178
• NCBI Protein Information: interferon-induced protein 44-like
• UniProt Protein Name: Interferon-induced protein 44-like
• Protein Family: Interferon-induced protein
• UniProt Gene Name: Ifi44l
• UniProt Synonym Gene Names: H28; HLA-HA28

NCBI Description

This gene encodes a minor histocompatibility antigen that is involved in tissue graft rejection and is polymorphic in different mouse strains. The 5' region of this gene, including the translational start codon and the first 293 amino acids, is absent from the C57BL/6J genome. The encoded antigen is not thought to be expressed in C57BL/6J. [provided by RefSeq, Mar 2013]

Uniprot Description

Precursor of the histocompatibility antigen HA-28 in BALB.B mice. More generally, minor histocompatibility antigens refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides to MHC molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD). More specifically, HA-28 minor antigen is transcribed in the BALB.B donor but not in host C57BL/6 cells. HA-28 is presented to the donor BALB.B cell surface by Kb MHC. This complex HA-28/Kb MHC elicits cytotoxic T-cell response in C57BL/6 mice immunized with BALB.B spleen cells. It induces C57BL/6 mice cells recognition and lysis by CD8 T-cell from BALB.B mice.