Gamma-interferon-inducible lysosomal thiol reductase (IFI30) Recombinant Protein | IFI30 recombinant protein
Recombinant Human Gamma-interferon-inducible lysosomal thiol reductase (IFI30)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008]
Uniprot Description
Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds (). Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation ().
Research Articles on IFI30
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Product Notes
The IFI30 ifi30 (Catalog #AAA1191047) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 58-232, Full length protein. The amino acid sequence is listed below: NAPLVNVTLY YEALCGGCRA FLIRELFPTW LLVMEILNVT LVPYGNAQEQ NVSGRWEFKC QHGEEECKFN KVEACVLDEL DMELAFLTIV CMEEFEDMER SLPLCLQLYA PGLSPDTIME CAMGDRGMQL MHANAQRTDA LQPPHEYVPW VTVNGKPLED QTQLLTLVCQ LYQGK. It is sometimes possible for the material contained within the vial of "Gamma-interferon-inducible lysosomal thiol reductase (IFI30), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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