Thyroglobulin Native Protein
Purified human thyroglobulin protein
Applications
SDS-Page, ELISA
Purity
>95% by SDS-PAGE
Synonyms
Thyroglobulin; Purified human thyroglobulin protein; TG; AITD 3; AITD3; hTG; TDH3; Tg; TGN; THYG; Thyroglobulin native protein
Host
Human Thyroid tissue (Negative for HBsAg, HCV, HIV-1 & HIV-2 by verifying)
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid
Applicable Applications for Thyroglobulin native protein
SDS-PAGE, ELISA (EIA)
Storage Buffer
Each vial contains 10 mM PBS, pH7.4 with 0.02% NaN3.
Preparation and Storage
Ship at 4 degree C. Upon receipt, aliquot and store at -20 degree C for long term. Avoid repeated freeze and thaw cycles.
Related Product Information for Thyroglobulin native protein
Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin protein accounts for approximately half of the protein content of the thyroid gland. Human TG is a homodimer of subunits each containing 2768 amino acids as synthesized (a short signal peptide may be removed from the N-terminus in the mature protein). Tg is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin has been shown to interact with Binding immunoglobulin protein.
References
1. Delom F, Mallet B, Carayon P, Lejeune PJ (June 2001). "Role of extracellular molecular chaperones in the folding of oxidized proteins. Refolding of colloidal thyroglobulin by protein disulfide isomerase and immunoglobulin heavy chain-binding protein". J. Biol. Chem. 276 (24): 21337–42.
2. Delom F, Lejeune PJ, Vinet L, Carayon P, Mallet B (February 1999). "Involvement of oxidative reactions and extracellular protein chaperones in the rescue of misassembled thyroglobulin in the follicular lumen". Biochem. Biophys. Res. Commun. 255 (2): 438–43.
2. Delom F, Lejeune PJ, Vinet L, Carayon P, Mallet B (February 1999). "Involvement of oxidative reactions and extracellular protein chaperones in the rescue of misassembled thyroglobulin in the follicular lumen". Biochem. Biophys. Res. Commun. 255 (2): 438–43.
NCBI and Uniprot Product Information
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Product Notes
The Thyroglobulin (Catalog #AAA355785) is a Native Protein produced from Human Thyroid tissue (Negative for HBsAg, HCV, HIV-1 & HIV-2 by verifying) and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Thyroglobulin can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, ELISA (EIA). Researchers should empirically determine the suitability of the Thyroglobulin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thyroglobulin, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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