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Human Transforming Growth Factor Beta 2 (TGFb2) RTU ELISA Kit | TGFb2 rtu elisa kit

Human Transforming Growth Factor Beta 2 (TGFb2) ELISA Kit

Gene Names
TGFB2; LDS4; G-TSF; TGF-beta2
Reactivity
Human
Synonyms
Transforming Growth Factor Beta 2 (TGFb2); Human Transforming Growth Factor Beta 2 (TGFb2) ELISA Kit; TGF-B2; TGF-Beta2; G-TSF; LAP; Cetermin; Polyergin; Latency-associated peptide; BSC-1 cell growth inhibitor; Glioblastoma-derived T-cell suppressor factor; TGFb2 rtu elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
442
Assay Type
Competitive Inhibition
Samples
Serum, Plasma, Tissue Homogenates, Cell Culture Supernates or Other Biological Fluids.
Detection Range
31.2-2000pg/mL
Sensitivity
8.64pg/mL
RTU ELISA Kit's Advantage
The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
Preparation and Storage
For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.
Related Product Information for TGFb2 rtu elisa kit
Test Principle: This assay employs the competitive inhibition enzyme immunoassay technique. A monoclonal antibody specific to TGFb2 has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled TGFb2 and unlabeled TGFb2 (Standards or samples) with the pre-coated antibody specific to TGFb2. After incubation the unbound conjugate is washed off. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. The amount of bound HRP conjugate is reverse proportional to the concentration of TGFb2 in the sample. After addition of the substrate solution, the intensity of color developed is reverse proportional to the concentration of TGFb2 in the sample.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,573 Da
NCBI Official Full Name
transforming growth factor beta-2 isoform 1
NCBI Official Synonym Full Names
transforming growth factor beta 2
NCBI Official Symbol
TGFB2
NCBI Official Synonym Symbols
LDS4; G-TSF; TGF-beta2
NCBI Protein Information
transforming growth factor beta-2
UniProt Protein Name
Transforming growth factor beta-2
UniProt Gene Name
TGFB2
UniProt Synonym Gene Names
TGF-beta-2; G-TSF; LAP

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]

Uniprot Description

TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

Research Articles on TGFb2

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Product Notes

The Human TGFb2 tgfb2 (Catalog #AAA4502818) is a RTU ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA4502818 RTU ELISA Kit recognizes Human TGFb2. It is sometimes possible for the material contained within the vial of "Transforming Growth Factor Beta 2 (TGFb2), RTU ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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