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Typical Testing Data/Standard Curve (for reference only)

Human Dermatan Sulfate Epimerase (DSE) RTU ELISA Kit | DSE rtu elisa kit

Human Dermatan Sulfate Epimerase (DSE) ELISA Kit

Gene Names
DSE; DSEP; DSEPI; SART2; EDSMC2; SART-2; DS-epi1
Reactivity
Human
Synonyms
Dermatan Sulfate Epimerase (DSE); Human Dermatan Sulfate Epimerase (DSE) ELISA Kit; DSEPI; SART2; Squamous Cell Carcinoma Antigen Recognized By T Cells 2; Chondroitin-glucuronate 5-epimerase; DSE rtu elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
958
Assay Type
Sandwich
Samples
Tissue Homogenates, Cell Lysates or Other Biological Fluids.
Detection Range
0.312-20ng/mL
Sensitivity
0.114ng/mL
RTU ELISA Kit's Advantage
The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
Preparation and Storage
For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for DSE rtu elisa kit
Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to DSE. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to DSE. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain DSE, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of DSE in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
109,773 Da
NCBI Official Full Name
dermatan-sulfate epimerase isoform a
NCBI Official Synonym Full Names
dermatan sulfate epimerase
NCBI Official Symbol
DSE
NCBI Official Synonym Symbols
DSEP; DSEPI; SART2; EDSMC2; SART-2; DS-epi1
NCBI Protein Information
dermatan-sulfate epimerase
UniProt Protein Name
Dermatan-sulfate epimerase
UniProt Gene Name
DSE
UniProt Synonym Gene Names
SART2; DS epimerase; SART-2

NCBI Description

The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016]

Uniprot Description

Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.

Research Articles on DSE

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Product Notes

The Human DSE dse (Catalog #AAA458933) is a RTU ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA458933 RTU ELISA Kit recognizes Human DSE. It is sometimes possible for the material contained within the vial of "Dermatan Sulfate Epimerase (DSE), RTU ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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