Human Anti-Mullerian Hormone (AMH) RTU ELISA Kit | AMH rtu elisa kit

Human Anti-Mullerian Hormone (AMH) ELISA Kit

Cat. Num. AAA457573

• Gene Names: AMH; MIF; MIS
• Reactivity: Human
• Synonyms: Anti-Mullerian Hormone (AMH); Human Anti-Mullerian Hormone (AMH) ELISA Kit; MIF; MIH; MIS; Müllerian Inhibiting Factor; Müllerian Inhibiting Hormone; Müllerian Inhibiting Substance; AMH rtu elisa kit

• Reactivity: Human
• Sequence Length: 560

• Assay Type: Competitive Inhibition
• Samples: Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates or Other Biological Fluids.
• Detection Range: 46.8-3000pg/mL
• Sensitivity: 23.2pg/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Related Product Information for AMH rtu elisa kit

Test Principle: technique. A monoclonal antibody specific to AMH has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled AMH and unlabeled AMH (Standards or samples) with the pre-coated antibody specific to AMH. After incubation the unbound conjugate is washed off. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. The amount of bound HRP conjugate is reverse proportional to the concentration of AMH in the sample. After addition of the substrate solution, the intensity of color developed is reverse proportional to the concentration of AMH in the sample.

NCBI and Uniprot Product Information

• NCBI GI #: 157266298
• NCBI GeneID: 268
• NCBI Accession #: NP_000470.2
• NCBI GenBank Nucleotide #: NM_000479.4
• UniProt Accession #: P03971; O75246; Q6GTN3
• Molecular Weight: 59,195 Da
• NCBI Official Full Name: muellerian-inhibiting factor preproprotein
• NCBI Official Synonym Full Names: anti-Mullerian hormone
• NCBI Official Symbol: AMH
• NCBI Official Synonym Symbols: MIF; MIS
• NCBI Protein Information: muellerian-inhibiting factor
• UniProt Protein Name: Muellerian-inhibiting factor
• Protein Family: Muellerian-inhibiting factor
• UniProt Gene Name: AMH
• UniProt Synonym Gene Names: MIF; AMH; MIS

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]

Uniprot Description

This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.