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Typical Testing Data/Standard Curve (for reference only)

Human Adenylate Cyclase 10, Soluble (ADCY10) RTU ELISA Kit | ADCY10 rtu elisa kit

Human Adenylate Cyclase 10, Soluble (ADCY10) ELISA Kit

Gene Names
ADCY10; SAC; HCA2; SACI; Sacy; hsAC; HEL-S-7a
Reactivity
Human
Synonyms
Adenylate Cyclase 10; Soluble (ADCY10); Human Adenylate Cyclase 10; Soluble (ADCY10) ELISA Kit; SAC; HCA2; SACI; Sacy; Testicular soluble adenylyl cyclase; Hypercalciuria; Absorptive 2; AH-related protein; Germ cell soluble adenylyl cyclase; ADCY10 rtu elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
1457
Assay Type
Sandwich
Samples
Tissue Homogenates or Other Biological Fluids.
Detection Range
0.156-10ng/mL
Sensitivity
0.051ng/mL
RTU ELISA Kit's Advantage
The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
Preparation and Storage
For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for ADCY10 rtu elisa kit
Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to ADCY10. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to ADCY10. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain ADCY10, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of ADCY10 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
169,750 Da
NCBI Official Full Name
adenylate cyclase type 10 isoform 2
NCBI Official Synonym Full Names
adenylate cyclase 10
NCBI Official Symbol
ADCY10
NCBI Official Synonym Symbols
SAC; HCA2; SACI; Sacy; hsAC; HEL-S-7a
NCBI Protein Information
adenylate cyclase type 10
UniProt Protein Name
Adenylate cyclase type 10
Protein Family
UniProt Gene Name
ADCY10
UniProt Synonym Gene Names
SAC; hsAC; sAC

NCBI Description

The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]

Uniprot Description

Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO2 levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (). Involved in ciliary beat regulation (PubMed:17591988).

Research Articles on ADCY10

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Product Notes

The Human ADCY10 adcy10 (Catalog #AAA4503439) is a RTU ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA4503439 RTU ELISA Kit recognizes Human ADCY10. It is sometimes possible for the material contained within the vial of "Adenylate Cyclase 10, Soluble (ADCY10), RTU ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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