KLF2 peptide
KLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF) Control Peptide
Highly purified (HPLC, MS)
Highly purified (HPLC, MS)
NCBI and Uniprot Product Information
NCBI Description
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]
Uniprot Description
Function: Binds to the CACCC box in the beta-globin gene promoter and activates transcription
By similarity.
Subunit structure: Interacts with WWP1. Ref.6
Subcellular location: Nucleus
By similarity.
Post-translational modification: Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein
By similarity.
Sequence similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.Contains 3 C2H2-type zinc fingers.
Research Articles on KLF2
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Product Notes
The KLF2 klf2 (Catalog #AAA659997) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. The KLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF) Control Peptide reacts with Human, Rodent and may cross-react with other species as described in the data sheet. AAA Biotech's KLF2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC). Suitable for use in ELISA, Antibody Blocking and other antigenic applications., Recommended Dilution:, Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the KLF2 klf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLF2, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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