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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using KCNJ2 antibody.)

anti-Human, Rat KCNJ2 Antibody | anti-KCNJ2 antibody

KCNJ2 Antibody

Gene Names
KCNJ2; IRK1; LQT7; SQT3; ATFB9; HHIRK1; KIR2.1; HHBIRK1
Reactivity
Human, Rat
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
KCNJ2; KCNJ2 Antibody; Inward rectifier potassium channel 2; Potassium channel; inwardly rectifying subfamily J member 2; Inward rectifier K(+) channel Kir2.1; Cardiac inward rectifier potassium channel; IRK1; anti-KCNJ2 antibody
Ordering
For Research Use Only!
Reactivity
Human, Rat
Specificity
KCNJ2 antibody detects endogenous levels of total KCNJ2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
427
Applicable Applications for anti-KCNJ2 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human KCNJ2.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using KCNJ2 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using KCNJ2 antibody.)
References
Raab-Graham K.F., Report 5:2501-2505(1994). Tang W., Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases. Wood L.S., Gene 163:313-317(1995).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,288 Da
NCBI Official Full Name
inward rectifier potassium channel 2
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily J member 2
NCBI Official Symbol
KCNJ2
NCBI Official Synonym Symbols
IRK1; LQT7; SQT3; ATFB9; HHIRK1; KIR2.1; HHBIRK1
NCBI Protein Information
inward rectifier potassium channel 2
UniProt Protein Name
Inward rectifier potassium channel 2
UniProt Gene Name
KCNJ2
UniProt Synonym Gene Names
IRK1; IRK-1; hIRK1

NCBI Description

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]

Uniprot Description

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

Research Articles on KCNJ2

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Product Notes

The KCNJ2 kcnj2 (Catalog #AAA855036) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The KCNJ2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KCNJ2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the KCNJ2 kcnj2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNJ2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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