Testing Data
(The TFact MEF2A (Phospho-Thr312) DNA-Binding ELISA detects active MEF2A (Phospho-Thr312) in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were stimulated by serum (20% FBS) before harvest.)
MEF2A elisa kit
MEF2A (Phospho-Thr312) TFact DNA-Binding ELISA Kit
Testing Data
(The TFact MEF2A (Phospho-Thr312) DNA-Binding ELISA detects active MEF2A (Phospho-Thr312) in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were stimulated by serum (20% FBS) before harvest.)
Testing Data
(The TFact MEF2A (Phospho-Thr312) DNA-Binding ELISA detects active MEF2A (Phospho-Thr312) in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were stimulated by serum (20% FBS) before harvest.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Uniprot Description
MEF2A: a myocyte-specific enhancing transcription factor which binds specifically to the MEF2 element present in the regulatory regions of many, if not all, muscle-specific genes. A member of the MADS gene family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain. Five alternatively spliced isoforms have been reported.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor
Chromosomal Location of Human Ortholog: 15q26.3
Cellular Component: cytosol; nuclear chromatin; nucleoplasm; nucleus; transcription factor complex
Molecular Function: activating transcription factor binding; chromatin binding; DNA binding transcription factor activity; histone acetyltransferase binding; histone deacetylase binding; protein binding; protein heterodimerization activity; protein kinase binding; sequence-specific DNA binding; SMAD binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Biological Process: apoptosis; cellular response to calcium ion; dendrite morphogenesis; ERK5 cascade; heart development; MAPK cascade; mitochondrial genome maintenance; mitochondrion distribution; muscle organ development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cardiac muscle hypertrophy; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription, DNA-dependent; ventricular cardiac myofibril assembly
Disease: Coronary Artery Disease, Autosomal Dominant, 1
Research Articles on MEF2A
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Product Notes
The Human, Mouse, Rat MEF2A mef2a (Catalog #AAA9502251) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502251 ELISA Kit recognizes Human, Mouse, Rat MEF2A. It is sometimes possible for the material contained within the vial of "MEF2A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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