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Testing Data (The TFact HBP1 DNA-Binding ELISA detects active HBP1 in Jurkat and MCF7 Nuclear Extract. The Jurkat and MCF7 cells were grown 3 days respectively in RPMI1640 and DMEM with 10% FBS and harvested for nuclear extract. )

HBP1 elisa kit

HBP1 TFact DNA-Binding ELISA Kit

Reactivity
Human, Mouse, Rat
Synonyms
HBP1; HBP1 TFact DNA-Binding ELISA Kit; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1; HBP1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
The TFact HBP1 DNA-Binding ELISA detects endogenous levels of total HBP1 protein.
Form/Format
12 x 8-Well Microstrips
Sequence Length
524
Samples
Cell lysate
Assay Type
DNA-Binding ELISA
Sensitivity
10-30 ug of total protein/well
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

Testing Data

(The TFact HBP1 DNA-Binding ELISA detects active HBP1 in Jurkat and MCF7 Nuclear Extract. The Jurkat and MCF7 cells were grown 3 days respectively in RPMI1640 and DMEM with 10% FBS and harvested for nuclear extract. )

Testing Data (The TFact HBP1 DNA-Binding ELISA detects active HBP1 in Jurkat and MCF7 Nuclear Extract. The Jurkat and MCF7 cells were grown 3 days respectively in RPMI1640 and DMEM with 10% FBS and harvested for nuclear extract. )

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,699 Da
NCBI Official Full Name
HMG box-containing protein 1 isoform 1
NCBI Official Synonym Full Names
HMG-box transcription factor 1
NCBI Official Symbol
HBP1
NCBI Protein Information
HMG box-containing protein 1
UniProt Protein Name
HMG box-containing protein 1
UniProt Gene Name
HBP1

Uniprot Description

HBP1: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 7q22.3

Cellular Component: nuclear speck; nucleoplasm

Molecular Function: DNA binding; protein binding; RNA binding

Biological Process: cell cycle arrest; regulation of transcription, DNA-templated; transcription, DNA-dependent; Wnt signaling pathway

Research Articles on HBP1

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Product Notes

The Human, Mouse, Rat HBP1 hbp1 (Catalog #AAA9502302) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502302 ELISA Kit recognizes Human, Mouse, Rat HBP1. It is sometimes possible for the material contained within the vial of "HBP1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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