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Testing Data

TNR16 Antibody | anti-TNR16 antibody

TNR16 Antibody

Gene Names
NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TNR16; TNR16 Antibody; Gp80-LNGFR; NGF receptor; TNFRSF16; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; p75 ICD; tumor necrosis factor receptor superfamily member 16; anti-TNR16 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
TNR16 antibody detects endogenous levels of total TNR16 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
427
Applicable Applications for anti-TNR16 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TNR16.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data

Western Blot (WB)

(Peptide-+ Western blot analysis of extracts from HepG2 cells, using TNR16 antibody. Immunofluorescence analysis of A549 cells, using TNR16 antibody.)

Western Blot (WB) (Peptide-+ Western blot analysis of extracts from HepG2 cells, using TNR16 antibody. Immunofluorescence analysis of A549 cells, using TNR16 antibody.)
References
Ye X., J. Biol. Chem. 274:30202-30208(1999). Wooten M.W., J. Biol. Chem. 276:7709-7712(2001). Bai D., Biochem. Biophys. Res. Commun. 309:552-557(2003).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,767 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 16
NCBI Official Synonym Full Names
nerve growth factor receptor
NCBI Official Symbol
NGFR
NCBI Official Synonym Symbols
CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR
NCBI Protein Information
tumor necrosis factor receptor superfamily member 16
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 16
UniProt Gene Name
NGFR
UniProt Synonym Gene Names
TNFRSF16; NGF receptor

NCBI Description

Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

Research Articles on TNR16

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Product Notes

The TNR16 ngfr (Catalog #AAA853464) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TNR16 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TNR16 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000. Researchers should empirically determine the suitability of the TNR16 ngfr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNR16, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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