Western Blot (WB)
(Western blot analysis of extracts from COLO cells, using STK39 (Ab-311) antibody.)
STK39 Antibody | anti-STK39 antibody
STK39 (Ab-311) Antibody
Gene Names
STK39; DCHT; PASK; SPAK
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
STK39; STK39 (Ab-311) Antibody; DCHT; EC 2.7.11.1; Serine/threonine-protein kinase 39; SPAK; Ste-20 related kinase; STE20/SPS1-related proline-alanine rich protein kinase; anti-STK39 antibody
Reactivity
Human, Mouse, Rat
Specificity
STK39 (Ab-311) antibody detects endogenous levels of total STK39 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
545
Applicable Applications for anti-STK39 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:40000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human STK39 around the phosphorylation site of serine 311 (G-K-SP-F-R).
Preparation and Storage
Store at-20 degree C for 1 year.
Western Blot (WB)
(Western blot analysis of extracts from COLO cells, using STK39 (Ab-311) antibody.)
Western Blot (WB)
(Western blot analysis of extracts from COLO cells, using STK39 (Ab-311) antibody.)
Product Categories/Family for anti-STK39 antibody
References
Johnston A.M., Oncogene 19:4290-4297(2000). Olsen J.V., Cell 127:635-648(2006). Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,937 Da
NCBI Official Full Name
STE20/SPS1-related proline-alanine-rich protein kinase
NCBI Official Synonym Full Names
serine/threonine kinase 39
NCBI Official Symbol
STK39
NCBI Official Synonym Symbols
DCHT; PASK; SPAK
NCBI Protein Information
STE20/SPS1-related proline-alanine-rich protein kinase
UniProt Protein Name
STE20/SPS1-related proline-alanine-rich protein kinase
Protein Family
UniProt Gene Name
STK39
UniProt Synonym Gene Names
SPAK; Ste-20-related kinase
NCBI Description
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
Uniprot Description
May act as a mediator of stress-activated signals. Mediates the inhibition of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation.
Research Articles on STK39
Similar Products
Product Notes
The STK39 stk39 (Catalog #AAA853511) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The STK39 (Ab-311) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's STK39 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:40000. Researchers should empirically determine the suitability of the STK39 stk39 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STK39, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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