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Immunohistochemistry (IHC)

RAB3IP Antibody | anti-RAB3IP antibody

RAB3IP Antibody

Gene Names
RAB3IP; RABIN3; RABIN8
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
RAB3IP; RAB3IP Antibody; Rabin-3; SSX2-interacting protein; anti-RAB3IP antibody
Ordering
 
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For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
RAB3IP antibody detects endogenous levels of total RAB3IP protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
254
Applicable Applications for anti-RAB3IP antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human RAB3IP.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using RAB3IP antibody.)

Product Categories/Family for anti-RAB3IP antibody
References
de Bruijn D.R.H., Genes Chromosomes Cancer 34:285-298(2002). Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,642 Da
NCBI Official Full Name
rab-3A-interacting protein isoform A
NCBI Official Synonym Full Names
RAB3A interacting protein
NCBI Official Symbol
RAB3IP
NCBI Official Synonym Symbols
RABIN3; RABIN8
NCBI Protein Information
rab-3A-interacting protein
UniProt Protein Name
Rab-3A-interacting protein
Protein Family
UniProt Gene Name
RAB3IP
UniProt Synonym Gene Names
Rab3A-interacting protein

Uniprot Description

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

Research Articles on RAB3IP

1. Authors show that Rab11-GMPPNP-FIP3-Rabin8 is more stable than Rab11-GMPPNP-Rabin8, owing to direct interaction between Rabin8 and FIP3 within the dual effector-bound complex.

Similar Products

RAB3IP Antibody

Host: n/a
Reactivity: n/a
Apps: n/a

RAB3IP Antibody

Host: Rabbit
Reactivity: Human, Mouse, Rat
Apps: Western Blot, Immunohistochemistry

Product Notes

The RAB3IP rab3ip (Catalog #AAA851364) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The RAB3IP Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAB3IP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:40000. Researchers should empirically determine the suitability of the RAB3IP rab3ip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB3IP, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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