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Western Blot (WB) (Western blot analysis of extracts from COLO cells, using PKR1 antibody.)

PKR1 Antibody | anti-PKR1 antibody

PKR1 Antibody

Gene Names
PROKR1; ZAQ; PKR1; GPR73; PK-R1; GPR73a
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PKR1; PKR1 Antibody; Prokineticin receptor 1; PK-R1; G-protein coupled receptor 73; GPR73a; G-protein coupled receptor ZAQ; PROKR1; GPR73; anti-PKR1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
PKR1 antibody detects endogenous levels of total PKR1 protein.
Purity/Purification
Affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
393
Applicable Applications for anti-PKR1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PKR1.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from COLO cells, using PKR1 antibody.)

Western Blot (WB) (Western blot analysis of extracts from COLO cells, using PKR1 antibody.)
References
Masuda Y., Biochem. Biophys. Res. Commun. 293:396-402(2002). Soga T., Biochim. Biophys. Acta 1579:173-179(2002). Lin D.C.-H., J. Biol. Chem. 277:19276-19280(2002).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,770 Da
NCBI Official Full Name
prokineticin receptor 1
NCBI Official Synonym Full Names
prokineticin receptor 1
NCBI Official Symbol
PROKR1
NCBI Official Synonym Symbols
ZAQ; PKR1; GPR73; PK-R1; GPR73a
NCBI Protein Information
prokineticin receptor 1
UniProt Protein Name
Prokineticin receptor 1
UniProt Gene Name
PROKR1
UniProt Synonym Gene Names
GPR73; PKR1; PK-R1

NCBI Description

This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]

Uniprot Description

Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.

Research Articles on PKR1

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Product Notes

The PKR1 prokr1 (Catalog #AAA852992) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The PKR1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PKR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the PKR1 prokr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKR1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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