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Western Blot (WB) (Western blot analysis of nNOS expression in HeLa cells)

nNOS Antibody | anti-nNOS antibody

nNOS Antibody

Gene Names
NOS1; NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS
Reactivity
Human, Mouse, Rat
Purity
Immunogen affinity purified
Synonyms
nNOS; nNOS Antibody; NOS1; BNOS; EC 1.14.13.39; IHPS1; N-NOS; NC-NOS; NNOS; NOS; anti-nNOS antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
nNOS Antibody detects endogenous levels of total nNOS
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1434
Immunogen
A synthesized peptide derived from human nNOS
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of nNOS expression in HeLa cells)

Western Blot (WB) (Western blot analysis of nNOS expression in HeLa cells)
Related Product Information for anti-nNOS antibody
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
125 kDa
NCBI Official Full Name
nitric oxide synthase, brain isoform 1
NCBI Official Synonym Full Names
nitric oxide synthase 1
NCBI Official Symbol
NOS1
NCBI Official Synonym Symbols
NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS
NCBI Protein Information
nitric oxide synthase, brain
UniProt Protein Name
Nitric oxide synthase, brain
UniProt Gene Name
NOS1
UniProt Synonym Gene Names
N-NOS; nNOS

NCBI Description

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]

Uniprot Description

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

Research Articles on nNOS

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Product Notes

The nNOS nos1 (Catalog #AAA8511760) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The nNOS Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "nNOS, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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