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Western Blot (WB) (Western blot analysis of extracts of mouse livertissue lysate, using NEUROG3 antibody. |Immunohistochemistryof paraffin-embeddedhuman thyroid cancer tissue usingNEUROG3antibody.)

NEUROG3 Antibody | anti-NEUROG3 antibody

NEUROG3 Antibody

Gene Names
NEUROG3; ngn3; Atoh5; NGN-3; Math4B; bHLHa7
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified
Synonyms
NEUROG3; NEUROG3 Antibody; ngn3; Atoh5; NGN-3; Math4B; bHLHa7; anti-NEUROG3 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
NEUROG3 Antibody detects endogenous levels of total NEUROG3
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
214
Applicable Applications for anti-NEUROG3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:100
Immunogen
Recombinant protein of human NEUROG3
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts of mouse livertissue lysate, using NEUROG3 antibody. |Immunohistochemistryof paraffin-embeddedhuman thyroid cancer tissue usingNEUROG3antibody.)

Western Blot (WB) (Western blot analysis of extracts of mouse livertissue lysate, using NEUROG3 antibody. |Immunohistochemistryof paraffin-embeddedhuman thyroid cancer tissue usingNEUROG3antibody.)
Related Product Information for anti-NEUROG3 antibody
Neurogenin-3 is a protein that in humans is encoded by the NEUROG3 gene. Neurogenin-3 is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix (bHLH) transcription factors involved in the determination of neural precursor cells in the neuroectoderm. The pancreas and brain the major splicing isoform does not code for a protein. Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23kDa
NCBI Official Full Name
neurogenin-3
NCBI Official Synonym Full Names
neurogenin 3
NCBI Official Symbol
NEUROG3
NCBI Official Synonym Symbols
ngn3; Atoh5; NGN-3; Math4B; bHLHa7
NCBI Protein Information
neurogenin-3
UniProt Protein Name
Neurogenin-3
Protein Family
UniProt Gene Name
NEUROG3
UniProt Synonym Gene Names
ATOH5; BHLHA7; NGN3; NGN-3; bHLHa7

NCBI Description

The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).[provided by RefSeq, May 2010]

Uniprot Description

Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types ().

Research Articles on NEUROG3

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Product Notes

The NEUROG3 neurog3 (Catalog #AAA8516519) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The NEUROG3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NEUROG3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:50-1:100. Researchers should empirically determine the suitability of the NEUROG3 neurog3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEUROG3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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