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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using LPHN2 antibody.Peptide: - / +)

LPHN2 Antibody | anti-LPHN2 antibody

LPHN2 Antibody

Gene Names
ADGRL2; CL2; LEC1; CIRL2; LPHH1; LPHN2
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
LPHN2; LPHN2 Antibody; Latrophilin-2; Calcium-independent alpha-latrotoxin receptor 2; Latrophilin homolog 1; Lectomedin-1; KIAA0786; LEC1; LPHH1; anti-LPHN2 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
LPHN2 antibody detects endogenous levels of total LPHN2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1403
Applicable Applications for anti-LPHN2 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human LPHN2.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using LPHN2 antibody.Peptide: - / +)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using LPHN2 antibody.Peptide: - / +)

Immunofluorescence (IF)

(Immunofluorescence analysis of COS-7 cells, using LPHN2 antibody. Peptide: - / + )

Immunofluorescence (IF) (Immunofluorescence analysis of COS-7 cells, using LPHN2 antibody. Peptide: - / + )
References
White G.R.M., Oncogene 17:3513-3519(1998). Gregory S.G., Nature 441:315-321(2006). Chen R., J. Proteome Res. 8:651-661(2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
adhesion G protein-coupled receptor L2 isoform 1 preproprotein
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor L2
NCBI Official Symbol
ADGRL2
NCBI Official Synonym Symbols
CL2; LEC1; CIRL2; LPHH1; LPHN2
NCBI Protein Information
adhesion G protein-coupled receptor L2
UniProt Protein Name
Adhesion G protein-coupled receptor L2
UniProt Gene Name
ADGRL2
UniProt Synonym Gene Names
CIRL-2

NCBI Description

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Description

Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.

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Product Notes

The LPHN2 adgrl2 (Catalog #AAA855933) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The LPHN2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LPHN2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50-1:100 IF: 1:100-1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the LPHN2 adgrl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LPHN2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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