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Testing Data (Peptide-+)

KCIP1 Antibody | anti-KCIP1 antibody

KCIP1 Antibody

Gene Names
KCNIP1; VABP; KCHIP1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
KCIP1; KCIP1 Antibody; Kv channel-interacting protein 1; KChIP1; A-type potassium channel modulatory protein 1; Potassium channel-interacting protein 1; Vesicle APC-binding protein; KCNIP1; KCHIP1; VABP; anti-KCIP1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
KCIP1 antibody detects endogenous levels of total KCIP1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
227
Applicable Applications for anti-KCIP1 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human KCIP1.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCIP1 antibody. Immunofluorescence analysis of HeLa cells, using KCIP1 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCIP1 antibody. Immunofluorescence analysis of HeLa cells, using KCIP1 antibody.)
References
An W.F., ure 403:553-556(2000). Van Hoorick D., Mol. Cell. Neurosci. 24:357-366(2003). Nakamura T.Y., FEBS Lett. 499:205-209(2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,842 Da
NCBI Official Full Name
Kv channel-interacting protein 1 isoform 1
NCBI Official Synonym Full Names
potassium voltage-gated channel interacting protein 1
NCBI Official Symbol
KCNIP1
NCBI Official Synonym Symbols
VABP; KCHIP1
NCBI Protein Information
Kv channel-interacting protein 1
UniProt Protein Name
Kv channel-interacting protein 1
UniProt Gene Name
KCNIP1
UniProt Synonym Gene Names
KCHIP1; VABP; KChIP1

NCBI Description

This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Uniprot Description

Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.

Research Articles on KCIP1

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Product Notes

The KCIP1 kcnip1 (Catalog #AAA859962) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The KCIP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KCIP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50-1:100 IF: 1:100-1:500 ELISA: 1:20000. Researchers should empirically determine the suitability of the KCIP1 kcnip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCIP1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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