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Immunohistochemistry (IHC) ((2ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

GSTM3 Antibody | anti-GSTM3 antibody

Goat anti-GSTM3 (aa47-60) Antibody

Gene Names
GSTM3; GST5; GSTB; GTM3; GSTM3-3
Reactivity
Mouse
Expected from sequence similarity: Human, Rat
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
GSTM3; Goat anti-GSTM3 (aa47-60) Antibody; Goat Anti-GSTM3 Antibody; glutathione S-transferase mu 3 (brain); GST5; GSTB; GSTM3-3; GTM3; GST class-mu 3; S-(hydroxyalkyl)glutathione lyase M3; brain GST; brain type mu-glutathione S-transferase; glutathione S-alkyltransferase M3; glutathione S-aralkyltransferase M3; glu; anti-GSTM3 antibody
Ordering
For Research Use Only!
Reactivity
Mouse
Expected from sequence similarity: Human, Rat
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Sequence Length
225
Applicable Applications for anti-GSTM3 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Pep-ELISA: antibody detection limit dilution 1:1000.
WB: Approx 28kDa band observed in Mouse Brain lysates. Recommended concentration: 1-3ug/ml.
Immunogen Sequence
Peptide with sequence C-RSQWLDVKFKLDLD, from the internal region of the protein sequence according to NP_000840.2.
Peptide Sequence + C
C-RSQWLDVKFKLDLD
Epitope
Internal Region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

((2ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Immunohistochemistry (IHC) ((2ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25.7kDa
NCBI Official Full Name
glutathione S-transferase Mu 3
NCBI Official Synonym Full Names
glutathione S-transferase mu 3
NCBI Official Symbol
GSTM3
NCBI Official Synonym Symbols
GST5; GSTB; GTM3; GSTM3-3
NCBI Protein Information
glutathione S-transferase Mu 3
UniProt Protein Name
Glutathione S-transferase Mu 3
Protein Family
UniProt Gene Name
GSTM3
UniProt Synonym Gene Names
GST5; hGSTM3-3

NCBI Description

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

Uniprot Description

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.

Research Articles on GSTM3

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Product Notes

The GSTM3 gstm3 (Catalog #AAA423814) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-GSTM3 (aa47-60) Antibody reacts with Mouse Expected from sequence similarity: Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GSTM3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Pep-ELISA: antibody detection limit dilution 1:1000. WB: Approx 28kDa band observed in Mouse Brain lysates. Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the GSTM3 gstm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GSTM3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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