GCLM Antibody | anti-GCLM antibody

GCLM Antibody

Cat. Num. AAA8516702

• Gene Names: GCLM; GLCLR
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Immunogen affinity purified
• Synonyms: GCLM; GCLM Antibody; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; anti-GCLM antibody

• Reactivity: Human, Mouse, Rat
• Specificity: GCLM Antibody detects endogenous levels of total GCLM
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 252

• Applicable Applications for anti-GCLM antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant protein of human GCLM
• Preparation and Storage: Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts of various celllines, using RAD51 antibody.)

Related Product Information for anti-GCLM antibody

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

NCBI and Uniprot Product Information

• NCBI GI #: 821325134
• NCBI GeneID: 2730
• NCBI Accession #: NP_001295182.1
• NCBI GenBank Nucleotide #: NM_001308253.1
• UniProt Accession #: P48507; Q6FHC1; Q9NPX9; Q9NU74; A8K334; D3DT45; M5A959
• Molecular Weight: 30kDa
• NCBI Official Full Name: glutamate--cysteine ligase regulatory subunit isoform 2
• NCBI Official Synonym Full Names: glutamate-cysteine ligase modifier subunit
• NCBI Official Symbol: GCLM
• NCBI Official Synonym Symbols: GLCLR
• NCBI Protein Information: glutamate--cysteine ligase regulatory subunit
• UniProt Protein Name: Glutamate--cysteine ligase regulatory subunit
• Protein Family: Glutamate--cysteine ligase regulatory
• UniProt Gene Name: GCLM
• UniProt Synonym Gene Names: GLCLR

NCBI Description

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]