CtBP2 Antibody | anti-CtBP2 antibody

CtBP2 Antibody

Cat. Num. AAA852586

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: CtBP2; CtBP2 Antibody; C-terminal-binding protein 2; CTBP2; anti-CtBP2 antibody

• Reactivity: Human, Mouse, Rat
• Specificity: CtBP2 antibody detects endogenous levels of total CtBP2 protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 445

• Applicable Applications for anti-CtBP2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:1000; ELISA: 1:1000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CtBP2.
• Preparation and Storage: Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HeLa cells and 293 cells, using CtBP2 antibody.)

Product Categories/Family for anti-CtBP2 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

References

Katsanis N., Genomics 47:294-299(1998). Schmitz F., Neuron 28:857-872(2000). Deloukas P., Nature 429:375-381(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 145580578
• NCBI GeneID: 1488
• NCBI Accession #: NP_001077383.1
• NCBI GenBank Nucleotide #: NM_001083914.2
• UniProt Accession #: P56545; O43449; Q5SQP7; Q69YI3; Q86SV0; Q8IY44; Q9H2T8; A8K2X5; D3DRF5
• Molecular Weight: 56,102 Da
• NCBI Official Full Name: C-terminal-binding protein 2 isoform 1
• NCBI Official Synonym Full Names: C-terminal binding protein 2
• NCBI Official Symbol: CTBP2
• NCBI Protein Information: C-terminal-binding protein 2
• UniProt Protein Name: C-terminal-binding protein 2
• Protein Family: C-terminal-binding protein
• UniProt Gene Name: CTBP2
• UniProt Synonym Gene Names: CtBP2

NCBI Description

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]

Uniprot Description

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation ().