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Testing Data (P-peptide-+)

CK-1 gamma 1/2/3 Antibody | anti-CK-1 gamma 1/2/3 antibody

CK-1 gamma 1/2/3 (Phospho-Tyr263) Antibody

Gene Names
CSNK1G1; CK1gamma1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Synonyms
CK-1 gamma 1/2/3; CK-1 gamma 1/2/3 (Phospho-Tyr263) Antibody; Casein kinase I; gamma 1 isoform; CK1-gamma1; CSNK1G1; EC 2.7.11.1; KC1G1; kinase CK1-gamma1; anti-CK-1 gamma 1/2/3 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody detects endogenous levels of CK-1 gamma 1/2/3 only when phosphorylated at tyrosine 263.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
422
Applicable Applications for anti-CK-1 gamma 1/2/3 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human CK-1 gamma 1/2/3 around the phosphorylation site of tyrosine 263 (E-R-YP-Q-K).
All Sites
Human: Tyr263/264/261
Mouse: Tyr263/264/261
Rat: Tyr263/264/261
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(P-peptide-+)

Testing Data (P-peptide-+)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human brain tissue using CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody. CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue using CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody. CK-1 gamma 1/2/3 (Phospho-Tyr263) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.)
References
Kusuda J., Cytogenet. Cell Genet. 90:298-302(2000). The MGC Project Team; Genome Res. 14:2121-2127(2004). Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,414 Da
NCBI Official Full Name
casein kinase I isoform gamma-1 isoform 1
NCBI Official Synonym Full Names
casein kinase 1 gamma 1
NCBI Official Symbol
CSNK1G1
NCBI Official Synonym Symbols
CK1gamma1
NCBI Protein Information
casein kinase I isoform gamma-1
UniProt Protein Name
Casein kinase I isoform gamma-1
UniProt Gene Name
CSNK1G1
UniProt Synonym Gene Names
CKI-gamma 1

NCBI Description

This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016]

Uniprot Description

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (). Phosphorylates CLSPN.

Research Articles on CK-1 gamma 1/2/3

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Product Notes

The CK-1 gamma 1/2/3 csnk1g1 (Catalog #AAA853070) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CK-1 gamma 1/2/3 (Phospho-Tyr263) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CK-1 gamma 1/2/3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:20000. Researchers should empirically determine the suitability of the CK-1 gamma 1/2/3 csnk1g1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CK-1 gamma 1/2/3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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