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Western Blot (WB) (Western blot analysis on 293 cell lysate using CBX6 Antibody)

CBX6 Antibody | anti-CBX6 antibody

CBX6 Antibody

Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified
Synonyms
CBX6; CBX6 Antibody; chromobox homolog 6; Chromobox protein homolog 6; anti-CBX6 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
CBX6 Antibody detects endogenous levels of CBX6
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
394
Applicable Applications for anti-CBX6 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human CBX6
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis on 293 cell lysate using CBX6 Antibody)

Western Blot (WB) (Western blot analysis on 293 cell lysate using CBX6 Antibody)
Related Product Information for anti-CBX6 antibody
CBX6 Involved in maintaining the transcriptionally repressive state of genes. Modifies chromatin, rendering it heritably changed in its expressibility (Probable). Component of the chromatin-associated polycomb complex (PcG). Note: This description may include information from UniProtKB.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44kDa
NCBI Official Full Name
chromobox protein homolog 6 isoform 2
NCBI Official Synonym Full Names
chromobox 6
NCBI Official Symbol
CBX6
NCBI Protein Information
chromobox protein homolog 6
UniProt Protein Name
Chromobox protein homolog 6
Protein Family
UniProt Gene Name
CBX6

Uniprot Description

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (). May have a PRC1-independent function in embryonic stem cells ().

Research Articles on CBX6

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Product Notes

The CBX6 cbx6 (Catalog #AAA8510878) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CBX6 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CBX6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CBX6 cbx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CBX6, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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