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Testing Data

Endomorphin 1 Antibody

Endomorphin 1, Affinity Purified Antibody

Reactivity
Human, Mouse, Primate, Rat
Applications
Immunohistochemistry
Synonyms
Endomorphin 1; Affinity Purified Antibody; anti-Endomorphin 1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Primate, Rat
Form/Format
Affinity Purified - Lyophilized
Applicable Applications for anti-Endomorphin 1 antibody
Immunohistochemistry (IHC)
Type Info
Rabbit IgG
Note
Our affinity-purified anti EM-1 antibodies label neuronal fibers in various brain regions including (but not limited to) thalamic nuclei, periaqueductal gray matter, amygdala, locus coeruleus, nucleus accumbens, parabrachial nucleus, nucleus tractus solitarius and septum. Our affinity-purified anti-END-2 antibodiy labelsl neuronal processes in spinal cord dorsal horn and trigeminal tract, and label neuronal cell bodies in thalamus. END-1 and 2 distribution in brain overlaps with mu-opioid receptors.
Immunogen
YPWF conjugated to BSA
Preparation and Storage
Store at 4-8 degrees

Testing Data

Testing Data
Related Product Information for anti-Endomorphin 1 antibody
Endomorphins are recently discovered endogenous opioid peptides composed of four amino acids: Endomorphin-1 (EM-1) is Tyr-Pro-Trp-Phe-NH2, and Endomorphin-2 (EM-2) is Tyr-Pro-Phe-Phe-NH2. These peptides have a very high affinity and specificity for mu-opioid receptors as it has been reported in many pharmacological studies. EM-1 is distributed in many brain regions, whereas EM-2 is prevalent in brainstem and spinal cord. EM-1 and EM-2 exert their antinociceptive activity by interacting with mu-opioid receptors. EM-1 anf EM-2 bind with mu-opioid receptor with high affinity and selectivity in comparison with binding to opioid delta and kappa receptors. EM-1 and EM-2 tetrapeptides activate G-proteins and inhibit adenylyl cyclase activity when bind to mu-opioid receptors.
Product Categories/Family for anti-Endomorphin 1 antibody

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Product Notes

The Endomorphin 1 (Catalog #AAA555205) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Endomorphin 1, Affinity Purified Antibody reacts with Human, Mouse, Primate, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Endomorphin 1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the Endomorphin 1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Endomorphin 1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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