Testing Data
(The TFact FKHRL1 (Phospho-Ser253) DNA-Binding ELISA detects active FKHRL1 (Phospho-Ser253) in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were Serum stimulated (20% FBS) before harvest.)
Human, Mouse FKHRL1 ELISA Kit | FKHRL1 elisa kit
FKHRL1 (Phospho-Ser253) TFact DNA-Binding ELISA Kit
Testing Data
(The TFact FKHRL1 (Phospho-Ser253) DNA-Binding ELISA detects active FKHRL1 (Phospho-Ser253) in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were Serum stimulated (20% FBS) before harvest.)
Testing Data
(The TFact FKHRL1 (Phospho-Ser253) DNA-Binding ELISA detects active FKHRL1 (Phospho-Ser253) in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were Serum stimulated (20% FBS) before harvest.)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Uniprot Description
FOXO3A: a transcription factors of the forkhead family. Contains 1 fork-head domain. May regulate apoptosis through control of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.
Protein type: Autophagy; DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: cytoplasm; cytosol; membrane; mitochondrion; nucleoplasm; nucleus
Molecular Function: beta-catenin binding; chromatin DNA binding; DNA binding; DNA binding transcription factor activity; protein binding; protein kinase binding; sequence-specific DNA binding
Biological Process: aging; anatomical structure morphogenesis; antral ovarian follicle growth; brain morphogenesis; cellular response to amyloid-beta; cellular response to corticosterone stimulus; cellular response to glucose stimulus; cellular response to hypoxia; cellular response to oxidative stress; DNA damage response, signal transduction by p53 class mediator; initiation of primordial ovarian follicle growth; negative regulation of canonical Wnt signaling pathway; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; oocyte maturation; ovulation from ovarian follicle; positive regulation of apoptosis; positive regulation of endothelial cell apoptotic process; positive regulation of erythrocyte differentiation; positive regulation of hydrogen peroxide-mediated programmed cell death; positive regulation of neuron apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; protein kinase B signaling; regulation of neural precursor cell proliferation; regulation of transcription from RNA polymerase II promoter; regulation of translation; response to dexamethasone; response to drug; response to nutrient levels; transcription from RNA polymerase II promoter; tumor necrosis factor-mediated signaling pathway
Research Articles on FKHRL1
Similar Products
Product Notes
The Human, Mouse FKHRL1 foxo3 (Catalog #AAA9502178) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502178 ELISA Kit recognizes Human, Mouse FKHRL1. It is sometimes possible for the material contained within the vial of "FKHRL1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
