Testing Data
(The TFact Elk1 (Phospho-Ser383) DNA-Binding ELISA detects active Elk1 (Phospho-Ser383) in Jurkat Nuclear Extract. The Jurkat cells were grown 3 days in RPMI 1640 with 10% FBS and harvested for nuclear extract. The DNA-transcription factor complex is treated with stablization buffer.)
Human, Mouse Elk1 ELISA Kit | ELK1 elisa kit
Elk1 (Phospho-Ser383) TFact DNA-Binding ELISA Kit
Testing Data
(The TFact Elk1 (Phospho-Ser383) DNA-Binding ELISA detects active Elk1 (Phospho-Ser383) in Jurkat Nuclear Extract. The Jurkat cells were grown 3 days in RPMI 1640 with 10% FBS and harvested for nuclear extract. The DNA-transcription factor complex is treated with stablization buffer.)
Testing Data
(The TFact Elk1 (Phospho-Ser383) DNA-Binding ELISA detects active Elk1 (Phospho-Ser383) in Jurkat Nuclear Extract. The Jurkat cells were grown 3 days in RPMI 1640 with 10% FBS and harvested for nuclear extract. The DNA-transcription factor complex is treated with stablization buffer.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]
Uniprot Description
ELK1: a transcription factor of the Ets family and the ternary complex factor (TCF) subfamily. Forms a ternary complex by binding to the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. Mediates gene activity in response to serum and growth factors. Phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus; phosphorylation at these sites is critical for transcriptional activation by Elk-1. Two alternatively-spliced isoforms have been described.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: axon terminus; cell soma; dendrite; mitochondrion; nucleoplasm; nucleus
Molecular Function: chromatin binding; DNA binding transcription factor activity; protein binding
Biological Process: cell differentiation; cellular response to gamma radiation; cellular response to testosterone stimulus; positive regulation of neuron death; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; response to fibroblast growth factor; response to light stimulus; transcription from RNA polymerase II promoter
Research Articles on ELK1
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Product Notes
The Human, Mouse ELK1 elk1 (Catalog #AAA9502154) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502154 ELISA Kit recognizes Human, Mouse ELK1. It is sometimes possible for the material contained within the vial of "Elk1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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