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Western Blot (WB) (Western blot analysis on Jurkat cell lysate using RIT1 Antibody)

anti-Human, Mouse RIT1 Antibody | anti-RIT1 antibody

RIT1 Antibody

Gene Names
RIT1; NS8; RIT; RIBB; ROC1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity-chromatography
Synonyms
RIT1; RIT1 Antibody; GTP-binding protein Rit1; GTP-binding protein Roc1; MGC125864; MGC125865; Ras-like protein expressed in many tissues; Ras-like without CAAX 1; Ras-like without CAAX protein 1; RIBB; Ric-like; expressed in many tissues; RIT; ROC1; anti-RIT1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
RIT1 antibody detects endogenous levels of total RIT1
Purity/Purification
Affinity-chromatography
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
183
Applicable Applications for anti-RIT1 antibody
Western Blot (WB)
Application Notes
WB: 1:500~1:3000
Immunogen
A synthesized peptide derived from human RIT1
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis on Jurkat cell lysate using RIT1 Antibody)

Western Blot (WB) (Western blot analysis on Jurkat cell lysate using RIT1 Antibody)
Related Product Information for anti-RIT1 antibody
RIT1 Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Belongs to the small GTPase superfamily. Ras family. Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25kDa
NCBI Official Full Name
GTP-binding protein Rit1 isoform 3
NCBI Official Synonym Full Names
Ras like without CAAX 1
NCBI Official Symbol
RIT1
NCBI Official Synonym Symbols
NS8; RIT; RIBB; ROC1
NCBI Protein Information
GTP-binding protein Rit1
UniProt Protein Name
GTP-binding protein Rit1
Protein Family
UniProt Gene Name
RIT1
UniProt Synonym Gene Names
RIBB; RIT; ROC1

NCBI Description

This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Uniprot Description

Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.

Research Articles on RIT1

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Product Notes

The RIT1 rit1 (Catalog #AAA8510744) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The RIT1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RIT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500~1:3000. Researchers should empirically determine the suitability of the RIT1 rit1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIT1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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