Western Blot (WB)
(Western blot analysis on mouse brain cell lysate using GAD1/2 Antibody)
anti-Human, Mouse GAD1/2 Antibody | anti-GAD1/2 antibody
GAD1/2 Antibody
Gene Names
GAD1; GAD; SCP; CPSQ1
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified
Synonyms
GAD1/2; GAD1/2 Antibody; 67 kDa glutamic acid decarboxylase; DCE1; FLJ45882; GAD; GAD-67; GAD1; GAD67; Glutamate decarboxylase 1; glutamate decarboxylase 1 (brain; 67kDa); Glutamate decarboxylase 67 kDa isoform; SCP 65 kDa glutamic acid decarboxylase; DCE2; GAD-65; GAD2; GAD65; anti-GAD1/2 antibody
Reactivity
Human, Mouse
Specificity
GAD1/2 Antibody detects endogenous levels of GAD1/2
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
594
Applicable Applications for anti-GAD1/2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
A synthesized peptide derived from human GAD1/2
Preparation and Storage
Store at-20 degree C for 1 year
Western Blot (WB)
(Western blot analysis on mouse brain cell lysate using GAD1/2 Antibody)
Western Blot (WB)
(Western blot analysis on mouse brain cell lysate using GAD1/2 Antibody)
Related Product Information for anti-GAD1/2 antibody
GAD2 Catalyzes the production of GABA. Homodimer. Belongs to the group II decarboxylase family. GAD67 Catalyzes the production of GABA. Homodimer. Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Belongs to the group II decarboxylase family. 3 isoforms of the human protein are produced by alternative splicing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65kDa
NCBI Official Full Name
glutamate decarboxylase 1 isoform GAD67
NCBI Official Synonym Full Names
glutamate decarboxylase 1
NCBI Official Symbol
GAD1
NCBI Official Synonym Symbols
GAD; SCP; CPSQ1
NCBI Protein Information
glutamate decarboxylase 1
UniProt Protein Name
Glutamate decarboxylase 1
UniProt Gene Name
GAD1
UniProt Synonym Gene Names
GAD; GAD67; GAD-67
NCBI Description
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
Uniprot Description
Catalyzes the production of GABA.
Research Articles on GAD1/2
Similar Products
Product Notes
The GAD1/2 gad1 (Catalog #AAA8511083) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The GAD1/2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GAD1/2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the GAD1/2 gad1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GAD1/2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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